1-((4-((2-(2-(7-Amino-4-methyl-1-oxo-1H-isochromen-3-yl)acetamido)ethyl)disulfanyl)butanoyl)oxy)-2, 5-dioxopyrrolidine-3-sulfonic acid is a linker for antibody-drug-conjugation (ADC).
Catalog Number | Size | Price | Quantity |
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BADC-00568 | -- | $-- |
1-((4-((2-(2-(7-Amino-4-Methyl-1-Oxo-1H-Isochromen-3-Yl)acetamido)ethyl)disulfanyl)butanoyl)oxy)-2,5-Dioxopyrrolidine-3-Sulfonic Acid, a complex compound with specific applications in bioscience and medical research, offers diverse possibilities in the following key areas with a high degree of perplexity and burstiness:
Protein Labeling and Modification: Delving into protein chemistry, this compound facilitates selective labeling and modification of proteins by targeting cysteine residues. It empowers the conjugation of fluorescent dyes or other functional groups to proteins, aiding in the exploration of protein structure and function. Employed in various biochemical assays and imaging techniques, this method offers invaluable insights into the intricacies of protein behavior.
Drug Delivery Systems: Boasting a unique chemical structure, this compound finds its niche in targeted drug delivery systems. By conjugating therapeutic agents to this compound, researchers engineer delivery mechanisms that precisely release drugs at the designated site of action. This targeted delivery strategy minimizes unwanted side effects and amplifies the efficacy of treatments, heralding a new era in personalized medicine.
Bioconjugation Chemistry: Serving as a pivotal reagent in bioconjugation reactions, this compound facilitates the formation of stable linkages between biomolecules—a cornerstone in biotechnology advancements. It plays a vital role in crafting antibody-drug conjugates (ADCs) for cancer therapy, seamlessly attaching cytotoxic drugs to antibodies. This innovative approach enhances the selectivity and potency of cancer treatments, offering hope in the fight against this formidable disease.
Enzyme Inhibition Studies: Researchers harness the power of this compound to delve into enzyme mechanisms and inhibition, unraveling the mysteries of enzymatic activity. Through the strategic modification of key amino acids in enzymes, scientists probe the enzyme's active site and study how inhibitors impact its function. This indispensable information guides the design of novel enzyme inhibitors with potential therapeutic applications, shedding light on new pathways in drug development.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.