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Fmoc-3VVD-OH is a cleavable ADC linker used to synthesize antibody-drug conjugations (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00695 | -- | $-- |
Fmoc-3VVD-OH, a fluorenylmethyloxycarbonyl (Fmoc) protected amino acid derivative, plays a pivotal role in peptide synthesis and biochemical research. Here are four key applications of Fmoc-3VVD-OH:
Peptide Synthesis: Essential in solid-phase peptide synthesis (SPPS), Fmoc-3VVD-OH facilitates the precise assembly of intricate peptide chains. The Fmoc group shields the amino terminal, safeguarding against undesirable reactions during synthesis. This meticulous process ensures the synthesis of peptides with pristine purity and accuracy, critical for a myriad of biochemical and pharmaceutical investigations.
Drug Development: Leveraging Fmoc-3VVD-OH within peptide libraries is instrumental in the exploration of novel therapeutic peptides possessing drug-like attributes. Researchers can design and evaluate diverse peptide sequences to screen for biological activity, binding affinity, and stability. This methodology expedites the identification and refinement of peptide-based drugs aimed at combating various diseases,.
Protein Engineering: In the realm of protein engineering, Fmoc-3VVD-OH is deployed to craft modified peptides and proteins endowed with distinctive properties and functions. By integrating this specific amino acid derivative into protein sequences, researchers introduce a spectrum of structural and functional diversity. These tailored proteins serve as invaluable tools for probing protein interactions, stability, and functionality across diverse biological contexts, enriching our understanding of protein behavior.
Bioconjugation: Fmoc-3VVD-OH plays a pivotal role in the development of peptide conjugates that link peptides to other molecules like drugs, probes, or nanoparticles. This conjugation enhances the specificity, delivery, and efficacy of therapeutic agents and diagnostic tools. Bioconjugates formulated with Fmoc-3VVD-OH find application in targeted drug delivery, imaging techniques, and biosensor technologies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
