Fmoc-N-amido-PEG6-propionic acid - CAS 882847-34-9
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Fmoc-N-amido-PEG6-propionic acid - CAS 882847-34-9 Catalog number: BADC-01185

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Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Fmoc-N-amido-PEG6-propionic acid
CAS
882847-34-9
Catalog Number
BADC-01185
Molecular Formula
C30H41NO10
Molecular Weight
575.65
Purity
≥95%
Fmoc-N-amido-PEG6-propionic acid

Ordering Information

Catalog Number Size Price Quantity
BADC-01185 -- $-- Inquiry

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Description
Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Fmoc-N-amido-PEG6-acid; Fmoc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid; 5,8,11,14,17,20-Hexaoxa-2-azatricosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-NH-PEG6-CH2CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid; (Fmoc-amino)-PEG6-carboxylic Acid; 21-(Fmoc-amino)-4,7,10,13,16,19-hexaoxahenicosanoic Acid; 21-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4,7,10,13,16,19-hexaoxahenicosanoic Acid
IUPAC Name
3-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI
InChI=1S/C30H41NO10/c32-29(33)9-11-35-13-15-37-17-19-39-21-22-40-20-18-38-16-14-36-12-10-31-30(34)41-23-28-26-7-3-1-5-24(26)25-6-2-4-8-27(25)28/h1-8,28H,9-23H2,(H,31,34)(H,32,33)
InChIKey
HEGZERUHBVYZPH-UHFFFAOYSA-N
Density
1.202±0.06 g/cm3 at 20°C, 760 Torr
Solubility
Soluble in DMSO (Slightly), Methanol (Slightly)
LogP
3.49030
PSA
131.01000
Appearance
Colorless to light yellow clear liquid
Shipping
Room temperature
Storage
Store at 2-8°C
Pictograms
Irritant
Signal Word
Warning
Boiling Point
734.8±60.0 °C at 760 mmHg
Biological Activity
Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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