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| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01066 | -- | $-- | Inquiry |
Mal-amido-PEG2-Val-Cit-PAB-PNP, a versatile linker molecule used in drug delivery and bioconjugation, plays a pivotal role in various applications.
Antibody-Drug Conjugates (ADCs): Mal-amido-PEG2-Val-Cit-PAB-PNP serves as a crucial link in the synthesis of antibody-drug conjugates. This linkage between a cytotoxic drug and an antibody ensures site-specific drug release at the tumor, minimizing systemic toxicity while maximizing therapeutic efficacy.
Controlled Drug Release: Enabling the design of advanced drug delivery systems, Mal-amido-PEG2-Val-Cit-PAB-PNP linkers provide a sophisticated approach to controlled drug release triggered by specific stimuli such as pH variations or enzymatic activity. The Val-Cit peptide sequence, susceptible to tissue-specific enzymes, allows for precise and controlled drug release at designated sites. This method enhances therapeutic efficacy while mitigating adverse effects, optimizing drug delivery for improved patient outcomes.
Pharmaceutical Research: A cornerstone of pharmaceutical research, this linker molecule facilitates exploration into the design and enhancement of drug delivery systems. Researchers leverage its flexibility to adjust properties by modifying PEG length or integrating additional functional groups, tailoring the linker for diverse therapeutic applications. This strategic customization enhances pharmacokinetic profiles and bolsters the stability of therapeutic agents, driving innovation in pharmaceutical sciences and advancing drug delivery technologies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
