Inquiry Basket
Gly-Gly-Gly-Gly-OH is a very versatile peptide mimetic compound. This cleavable linker stands out through its careful design in complex drug delivery systems, promising profound implications in the fight against a variety of diseases including cancer, neurodegenerative diseases, and cardiovascular diseases.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01587 | -- | $-- | Inquiry |
Gly-Gly-Gly-Gly-OH is a tetrapeptide composed of four glycine units and serves as an important building block in peptide synthesis and molecular design. Its small size and simple structure make it a versatile compound in drug development, particularly in the creation of peptide-based therapeutics. This tetrapeptide can be used to explore structure-activity relationships and optimize the stability and bioavailability of larger peptides. Additionally, Gly-Gly-Gly-Gly-OH is often employed as a spacer or linker in drug conjugates, where it can help in improving the pharmacokinetic properties of the conjugated drugs, ensuring that the therapeutic agents are delivered efficiently to target tissues.
Another key application of Gly-Gly-Gly-Gly-OH lies in the field of peptide-drug conjugates (PDCs). As a simple, non-toxic sequence, it is used to connect active pharmaceutical compounds to target-specific peptides or antibodies. This allows for the selective delivery of drugs to particular tissues, enhancing the therapeutic effect while minimizing systemic side effects. The tetrapeptide's ability to link payloads with high stability yet cleave in response to specific biological conditions, such as enzyme activity, makes it an ideal candidate for the controlled release of cytotoxic agents or other therapeutic molecules within targeted cells. This approach is particularly valuable in cancer therapy, where precise drug delivery is essential.
Additionally, Gly-Gly-Gly-Gly-OH plays a role in research related to protein folding and molecular recognition. Its repetitive glycine structure is useful for studying the behavior of peptides in different environments and their interactions with other molecules. By varying the number of glycine residues or incorporating different amino acids, researchers can investigate how peptide sequences affect protein conformation and binding affinity. This has applications in drug design, biomaterials, and the development of biosensors, where precise molecular interactions are crucial for performance. In this regard, Gly-Gly-Gly-Gly-OH serves as a foundational tool in advancing both basic and applied biochemistry.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
