Hydroxy-PEG3-DBCO - CAS 2566404-76-8 Catalog number: BADC-01684

Hydroxy-PEG3-DBCO, a versatile bi-functional reagent, finds widespread applications in the realm of bioconjugation chemistry. Here are four key applications of Hydroxy-PEG3-DBCO:

Bioorthogonal Chemistry: At the forefront of modern research, Hydroxy-PEG3-DBCO is a cornerstone in bioorthogonal chemical reactions that enable precise labeling of biomolecules within intricate biological settings while preserving natural processes. Its specific reactivity with azide groups positions it as an invaluable asset for click chemistry applications, empowering researchers to label proteins, DNA, or nucleic acids for in-depth exploration of molecular interactions and dynamics within cellular environments.

Drug Delivery Systems: In drug delivery, Hydroxy-PEG3-DBCO emerges as a pivotal player, facilitating the creation of targeted drug delivery systems. By linking therapeutic agents to the DBCO moiety, scientists can engineer drug conjugates that selectively target specific cells or tissues, elevating drug efficacy while mitigating side effects.

Diagnostics and Imaging: Hydroxy-PEG3-DBCO serves as a linchpin in the formulation of diagnostic probes and imaging agents. When conjugated with fluorophores or radiolabeled compounds, it empowers precise labeling of biomolecules for visualization in biological studies. This application is instrumental in driving forward techniques such as fluorescence microscopy, PET, and MRI.

Surface Functionalization: In the arena of surface modification, Hydroxy-PEG3-DBCO stands out as a key tool for functionalizing biomaterials and nanoparticles. By affixing DBCO groups to surfaces, researchers can finely tune and regulate interaction properties with cells and biomolecules.