Hydroxy-PEG2-t-butyl ester - CAS 133803-81-3

Hydroxy-PEG2-t-butyl ester - CAS 133803-81-3 Catalog number: BADC-00926

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Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).

Category
ADCs Linker
Product Name
Hydroxy-PEG2-t-butyl ester
CAS
133803-81-3
Catalog Number
BADC-00926
Molecular Formula
C11H22O5
Molecular Weight
234.29
Hydroxy-PEG2-t-butyl ester

Ordering Information

Catalog Number Size Price Quantity
BADC-00926 -- $--
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Description
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).
Synonyms
HO-PEG2-CH2CH2COOtBu; Hydroxy-PEG2-(CH2)2-Boc; OH-PEG2-TBA; OH-PEG2-CH2CH2COOtBu; HO-PEG2-t-butyl ester; Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester; t-Butyl 9-hydroxy-4,7-dioxanonanoate; 3-[2-(2-hydroxyethoxy)ethoxy]propionic acid t-butyl ester; 2-Methyl-2-propanyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
IUPAC Name
tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCO
InChI
InChI=1S/C11H22O5/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h12H,4-9H2,1-3H3
InChIKey
OKOWESVURLUVMD-UHFFFAOYSA-N
Density
1.046±0.1 g/cm3
Solubility
Soluble in DMSO (10 mm)
LogP
0.74370
PSA
64.99000
Biological Activity
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2- (CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Pale Yellow or Colorless Oily Liquid
Purity
≥95%
Shipping
Room temperature
Storage
Store at 2-8°C
Boiling Point
321.8±22.0 °C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Hydroxy-PEG2-t-butyl ester
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