Hydroxy-PEG3-t-butyl ester - CAS 186020-66-6
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Hydroxy-PEG3-t-butyl ester - CAS 186020-66-6 Catalog number: BADC-01015

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Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Hydroxy-PEG3-t-butyl ester
CAS
186020-66-6
Catalog Number
BADC-01015
Molecular Formula
C13H26O6
Molecular Weight
278.34
Hydroxy-PEG3-t-butyl ester

Ordering Information

Catalog Number Size Price Quantity
BADC-01015 -- $--
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Description
Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
HO-PEG3-CH2CH2COOtBu; Hydroxy-PEG3-(CH2)2-Boc; OH-PEG3-TBA; OH-PEG3-CH2CH2COOtBu; HO-PEG3-t-butyl ester; tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate; 3-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester; 12-Hydroxy-4,7,10-trioxadodecanoic Acid tert-Butyl Ester; 2-Methyl-2-propanyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate; Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester; tert-Butyl triethylene glycol-O-propionate
IUPAC Name
tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCO
InChI
InChI=1S/C13H26O6/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h14H,4-11H2,1-3H3
InChIKey
KSXVEOLRERRELV-UHFFFAOYSA-N
Density
1.052 g/mL at 20°C
Solubility
Soluble in DMSO (10 mm)
Flash Point
125.2°C
Index Of Refraction
1.45
LogP
0.76030
PSA
74.22000
Vapor Pressure
7.78E-07mmHg at 25°C
Biological Activity
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2- (CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Colorless to light yellow to light orange clear liquid
Purity
≥95%
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C
Boiling Point
365.8±27.0°C (Predicted)
Form
Liquid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

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Historical Records: Hydroxy-PEG3-t-butyl ester
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