N-Succinimidyl 3-(Bromoacetamido)propionate - CAS 57159-62-3

N-Succinimidyl 3-(Bromoacetamido)propionate - CAS 57159-62-3 Catalog number: BADC-01139

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N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
N-Succinimidyl 3-(Bromoacetamido)propionate
CAS
57159-62-3
Catalog Number
BADC-01139
Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10
N-Succinimidyl 3-(Bromoacetamido)propionate

Ordering Information

Catalog Number Size Price Quantity
BADC-01139 -- $--
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Description
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate; Succinimidyl-3-(bromoacetamido)propionate; 3-(2-bromoacetamido)propanoic acid NHS ester
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[(2-bromoacetyl)amino]propanoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCNC(=O)CBr
InChI
InChI=1S/C9H11BrN2O5/c10-5-6(13)11-4-3-9(16)17-12-7(14)1-2-8(12)15/h1-5H2,(H,11,13)
InChIKey
WGMMKWFUXPMTRW-UHFFFAOYSA-N
Density
1.69 g/cm3
Solubility
10 mm in DMSO
Melting Point
93-94°C
Index Of Refraction
1.566
PSA
92.78000
Appearance
Off-white to white waxy solid
Purity
>99.3%
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Pictograms
Irritant
Signal Word
Warning
Form
Solid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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