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(S,E)-TCO2-PEG4-NHS ester is an ADC linker containing 4 PEG units.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01905 | -- | $-- | Inquiry |
(S,E)-TCO2-PEG4-NHS ester, a versatile chemical linker utilized in diverse bioscience applications, plays a pivotal role in various key applications characterized by high perplexity and burstiness.
Bioconjugation: (S,E)-TCO2-PEG4-NHS ester serves as a fundamental tool in bioconjugation, facilitating the linkage of biomolecules like proteins, peptides, and antibodies through the formation of stable amide bonds with primary amines. This intricate process enables targeted delivery and enhanced solubility of therapeutic molecules, essential for advancing antibody-drug conjugates and diagnostic assays towards groundbreaking discoveries.
Drug Delivery: The incorporation of the hydrophilic PEG segment in (S,E)-TCO2-PEG4-NHS ester elevates the solubility and biocompatibility of drug molecules, making it a preferred choice for modifying drug carriers such as liposomes and nanoparticles. This enhancement optimizes circulation time and diminishes immunogenicity, resulting in more effective and precise drug delivery mechanisms with profound implications for medical advancements.
Surface Modification: Leveraging (S,E)-TCO2-PEG4-NHS ester for surface modification of medical devices and biosensors introduces antifouling properties and diminishes non-specific binding, crucial for enhancing device performance and durability. By creating a hydrophilic barrier through PEG chain attachment, the linker resists protein adsorption and cell adhesion, thus revolutionizing the landscape of implants and diagnostic devices with a focus on longevity and efficacy.
Proteomics and Protein Labeling: In the realm of proteomic studies, (S,E)-TCO2-PEG4-NHS ester emerges as a pivotal component for protein labeling, enabling researchers to identify and quantify proteins with precision. Through covalent attachment of fluorescent dyes or affinity tags, scientists gain insights into protein interactions, post-translational modifications, and expression levels, thereby unlocking high-throughput screening capabilities and deepening the comprehension of intricate biological systems.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
