2, 5-Dioxopyrrolidin-1-yl 3-((2-fluorobenzyl)oxy)propanoate is a linker for antibody-drug-conjugation (ADC).
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BADC-00521 | -- | $-- | Inquiry |
2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate is primarily utilized in the field of pharmaceuticals and medicinal chemistry. This compound plays a crucial role as an intermediate in the synthesis of various therapeutic agents. It is often employed in the preparation of drugs that target specific enzymes or receptors, thereby altering biological pathways to treat diseases such as cancer, inflammation, and neurological disorders. The presence of the 2-fluorobenzyl group enhances the compound’s pharmacokinetic properties, thus improving the efficacy and bioavailability of the resulting pharmaceuticals.
Another significant application of 2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate is in the field of organic synthesis, particularly in the creation of complex molecular structures. Due to its reactive 2,5-dioxopyrrolidin-1-yl group, this compound serves as a versatile building block for constructing a variety of organic molecules. Its stability and reactivity make it an excellent candidate for forming carbon-oxygen and carbon-nitrogen bonds, which are essential in the production of fine chemicals, agrochemicals, and other specialized organic compounds. This utility in synthetic chemistry underlines its importance in both academic research and industrial applications.
In the realm of polymer chemistry, 2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate is employed in the development of advanced polymeric materials. This compound can be incorporated into polymer backbones, where its functional groups allow for further chemical modifications and cross-linking. The resulting polymers often exhibit enhanced mechanical properties, thermal stability, and resistance to chemical degradation, making them suitable for use in a wide range of applications, including biomedical devices, coatings, and advanced composites. These attributes make it a valuable monomer in the synthesis of high-performance materials.
Finally, 2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate finds application in the field of bioconjugation and molecular tagging. Its reactive functional groups enable it to form stable covalent bonds with various biomolecules, such as proteins, nucleic acids, and small molecules. This capability is essential for the development of diagnostic tools, therapeutic agents, and targeted drug delivery systems. By attaching to specific biological targets, it allows for precise monitoring and manipulation of biological processes, which is crucial in both laboratory research and clinical applications. This versatility underscores its importance in the burgeoning field of chemical biology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.