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| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01258 | -- | $-- |
Diazo Biotin-PEG3-DBCO, a versatile chemical linker employed in bioconjugation applications, offers a myriad of uses. Here are four key applications of Diazo Biotin-PEG3-DBCO:
Protein Labelling: Diazo Biotin-PEG3-DBCO finds widespread utility in the labeling of proteins for biochemical assays. The incorporation of the biotin moiety enables precise and efficient binding to streptavidin or avidin-coated surfaces, facilitating the isolation and analysis of target proteins. This application is particularly valuable in immunoassays, Western blotting, and protein purification protocols, enabling researchers to delve into the intricacies of protein function with unparalleled depth.
Live Cell Imaging: Within the realm of live cell imaging, Diazo Biotin-PEG3-DBCO serves as a crucial tool for tagging biomolecules with fluorescent labels. The DBCO group’s interaction with azide-functionalized fluorescent probes via bioorthogonal click chemistry ensures minimal disruption to cellular function, permitting the visualization and tracking of dynamic processes within living cells with exquisite detail. This advanced imaging technique opens new avenues for studying cell behavior and molecular dynamics in real time.
Drug Delivery: Leveraging the capabilities of Diazo Biotin-PEG3-DBCO, researchers are revolutionizing targeted drug delivery systems. The biotin-PEG linkage facilitates the attachment of therapeutic agents to biotinylated carriers, such as antibodies or nanoparticles, enhancing the selectivity and efficiency of drug delivery to specific tissues or cell types. This innovative approach holds the potential to significantly improve therapeutic outcomes by precisely delivering drugs to their intended targets, minimizing off-target effects, and maximizing treatment efficacy.
Biosensor Development: In the realm of biosensor development, Diazo Biotin-PEG3-DBCO plays a pivotal role in surface modification for enhanced sensing capabilities. The biotin group acts as a key component for capturing biotinylated recognition elements like antibodies or aptamers onto sensor surfaces, enabling sensitive and specific detection of analytes in diverse diagnostic and environmental monitoring applications. This sophisticated biosensing approach offers researchers unprecedented insights into complex biological and environmental processes, driving forward innovation in the field of biosensors.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
