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Dimethylamine-SPDB is a small molecule biopharmaceutical compound. It inhibits viral replication and pathogenesis by targeting enzymes, demonstrating its prowess as a powerful antagonist of viral infections, including influenza and hepatitis. Furthermore, it holds great promise in the field of oncology, fighting malignant tumors by elastically destroying the growth and proliferation of malignant cells.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00476 | -- | $-- |
2,5-Dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate is primarily utilized in the field of organic chemistry for the formation of peptide-bond analogs. This compound acts as a coupling reagent, facilitating the synthesis of peptides by forming amide bonds between amino acids. The presence of its disulfide linkage and dimethylamino moiety enhances its reactivity and selectivity in peptide synthesis, making it a valuable tool for chemists working to create complex biomolecules. Its application in peptide synthesis is critical for the development of therapeutic peptides and research peptides that have potential uses in treating various diseases and understanding biological processes.
Another significant application of 2,5-Dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate is in the synthesis of bioconjugates. This compound’s unique structural features, especially the reactive disulfide bond, enable it to link bioactive molecules, such as enzymes or antibodies, to other functional entities, such as drug molecules or imaging agents. These bioconjugates are crucial in targeted drug delivery systems and diagnostic tools, allowing for precise targeting of therapeutic agents to specific cells or tissues, thereby improving efficacy and reducing side effects.
In the realm of medicinal chemistry, 2,5-Dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate is employed in the development of prodrugs. The compound’s disulfide bond can be strategically cleaved in the reductive environment inside cells, releasing the active drug. This targeted activation mechanism is particularly important for developing therapies with improved pharmacokinetic and pharmacodynamic profiles. The design of prodrugs using this compound helps in achieving better absorption, distribution, metabolism, and excretion properties, aligned with the specific therapeutic needs.
Finally, 2,5-Dioxopyrrolidin-1-yl 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate is used in the field of chemical biology to create probes for studying biological systems. These probes can interact with specific proteins or nucleic acids, providing insights into cellular mechanisms and pathways. The compound’s potential to form stable yet selectively cleavable linkages makes it ideal for designing probes that can be activated or deactivated in response to specific cellular conditions, facilitating a better understanding of cellular dynamics, protein interactions, and intracellular signaling. Such probes are invaluable in basic research, drug discovery, and the development of new therapeutic strategies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
