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2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester) is a macrocyclic DOTA derivative for tumor pretargeting.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00989 | -- | $-- | Inquiry |
2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester) serves as a versatile chelating agent with diverse scientific applications, notably in the realm of medical imaging and radiopharmaceuticals. Here are four key applications presented with high perplexity and burstiness:
Radiopharmaceutical Development: This compound plays a pivotal role in chelating radioactive isotopes essential for diagnostic imaging and radiotherapy. By binding with isotopes like ^68Ga or ^177Lu, it facilitates the creation of radiopharmaceuticals tailored to target specific tissues or tumors. These radiopharmaceuticals stand as indispensable tools in cancer diagnosis, treatment planning, and therapeutic efficacy monitoring.
MRI Contrast Agents: Leveraging 2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester), researchers can synthesize MRI contrast agents by chelating gadolinium ions. This process enhances the visibility of blood vessels, tissues, and organs during MRI scans, significantly enhancing the accuracy of diagnostic imaging and aiding in the early detection of diseases.
Peptide and Antibody Labeling: Frequently utilized for labeling peptides and antibodies with metal ions in various biomedical applications, this compound enables targeted delivery of diagnostic and therapeutic agents to specific biological targets. Such targeted delivery holds particular significance in the realm of personalized medicine for conditions like cancer and autoimmune disorders.
Biomedical Research: Widely incorporated in research studies focusing on metal ion chelation, 2-Aminoethyl-mono-amide-DOTA-tris(t-Bu ester) contributes to the development of new diagnostic tools and therapeutic strategies by facilitating precise metal delivery to biological molecules. Researchers harness this compound to explore novel avenues in molecular imaging, drug delivery, and nanomedicine, pushing the boundaries of biomedical research and innovation.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
