(Ac)Phe-Lys(Alloc)-PABC-PNP - CAS 2070009-39-9

(Ac)Phe-Lys(Alloc)-PABC-PNP - CAS 2070009-39-9 Catalog number: BADC-01529

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Category
ADCs Linker
Product Name
(Ac)Phe-Lys(Alloc)-PABC-PNP
CAS
2070009-39-9
Catalog Number
BADC-01529
Molecular Formula
C35H39N5O10
Molecular Weight
689.71
(Ac)Phe-Lys(Alloc)-PABC-PNP

Ordering Information

Catalog Number Size Price Quantity
BADC-01529 -- $-- Inquiry
Synonyms
(Ac)Phe-Lys(Alloc)-PABC-PNP; [4-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-6-(prop-2-enoxycarbonylamino)hexanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
Canonical SMILES
CC(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCCNC(=O)OCC=C)C(=O)NC2=CC=C(C=C2)COC(=O)OC3=CC=C(C=C3)[N+](=O)[O-]
InChI
InChI=1S/C35H39N5O10/c1-3-21-48-34(44)36-20-8-7-11-30(39-33(43)31(37-24(2)41)22-25-9-5-4-6-10-25)32(42)38-27-14-12-26(13-15-27)23-49-35(45)50-29-18-16-28(17-19-29)40(46)47/h3-6,9-10,12-19,30-31H,1,7-8,11,20-23H2,2H3,(H,36,44)(H,37,41)(H,38,42)(H,39,43)/t30-,31-/m0/s1
InChIKey
SGYSBXZWQCUJQV-CONSDPRKSA-N
Storage
solvent: -80°C 12 months; Powder: -20°C 3 years

Prodrug Development: (Ac)Phe-Lys(Alloc)-PABC-PNP emerges as a cornerstone in the realm of prodrug design and synthesis, harnessing its stable and biocompatible properties. Through the seamless integration of this versatile compound into formulations, researchers craft prodrugs that strategically release their active pharmaceutical ingredients precisely at predetermined target sites. This sophisticated delivery approach not only magnifies therapeutic efficacy but also elegantly mitigates undesirable side effects, heralding a new era of precision in drug administration.

Enzyme Substrate Assays: Serving as a synthetic substrate in the intricate realm of enzyme activity analyses, (Ac)Phe-Lys(Alloc)-PABC-PNP undergoes precise cleavage by specific proteases, enabling real-time monitoring of enzyme kinetics and specificity. This pivotal application plays a central role in dissecting enzyme functionalities and designing potent enzyme inhibitors, shedding illuminating insights into the elaborate mechanisms governing enzymatic processes.

Molecular Probing: Embracing (Ac)Phe-Lys(Alloc)-PABC-PNP as a sophisticated molecular probe opens doors to in-depth investigations into protein-protein interactions and post-translational modifications. By skillfully tagging proteins of interest with this compound, scientists can trace interactions and modifications through discernible alterations in fluorescence or other distinctive signals, delving deep into the intricate pathways and mechanisms that characterize cellular signaling with finesse.

Bioconjugation: In the realm of cutting-edge bioconjugation strategies, (Ac)Phe-Lys(Alloc)-PABC-PNP emerges as a pivotal linker, seamlessly uniting diverse biomolecules such as antibodies, peptides, or nucleic acids. This seamless integration leads to the creation of multifunctional bioconjugates, customized for targeted drug delivery, imaging, or therapeutic applications. Leveraging the unique properties of (Ac)Phe-Lys(Alloc)-PABC-PNP in bioconjugation not only enhances the precision and versatility of biomolecular tools across a myriad of biomedical arenas but also catalyzes a revolution in the landscape of targeted interventions.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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