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Ald-Ph-amido-PEG2-C2-Pfp ester is a PEGn linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00652 | -- | $-- |
Ald-Ph-amido-PEG2-C2-Pfp ester, a versatile chemical reagent in the realms of bioconjugation and drug delivery, finds wide-ranging applications. Here are four key applications presented with high perplexity and burstiness:
Protein Labeling: Through its interactions with amino groups on proteins, Ald-Ph-amido-PEG2-C2-Pfp ester emerges as a pivotal tool for labeling proteins with various entities such as fluorophores, biotin, or other tags. These stable amide bonds serve as the foundation for protein tracking, facilitating localization studies and delving into protein-protein interactions with intricate detail.
Drug Delivery: Leveraging the abilities of the ester, researchers can delve into the realm of PEGylation to enhance the solubility, stability, and half-life of drugs. By coupling therapeutic molecules to the PEG chain, the efficacy of drugs is amplified and immunogenicity is dampened. This approach proves particularly advantageous for biologics and peptide-based therapeutics, ushering in a new era of drug delivery innovations.
Surface Modification: Ald-Ph-amido-PEG2-C2-Pfp ester plays a pivotal role in the modification of surfaces on nanoparticles, implants, and biomaterials. By introducing polyethylene glycol (PEG) chains, nonspecific protein adsorption is minimized and biocompatibility is heightened. This intricate application forms the cornerstone for the development of cutting-edge medical devices and advanced therapeutic nanocarriers, pushing the boundaries of biotechnology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
