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Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01214 | -- | $-- |
Amino-PEG6-amido-bis-PEG5-N3 is a multifunctional polymer utilized in bioconjugation, drug delivery, and various other biomedical applications. Here are some key applications of Amino-PEG6-amido-bis-PEG5-N3:
Bioconjugation: Amino-PEG6-amido-bis-PEG5-N3 serves as a versatile linker in the conjugation of biomolecules, such as proteins, antibodies, and nucleic acids. By connecting different functional units, it facilitates the creation of sophisticated bioconjugates for diagnostics or therapeutic purposes. The PEG (polyethylene glycol) spacers enhance solubility and reduce immunogenicity of the conjugates.
Drug Delivery: In drug delivery systems, Amino-PEG6-amido-bis-PEG5-N3 is used to improve the solubility, stability, and bioavailability of pharmaceutical agents. The polymer's PEG chains offer stealth properties, reducing the recognition by the immune system and extending the circulation time of drug-loaded nanoparticles. This results in more effective and targeted delivery of drugs to diseased tissues.
Surface Modification: Amino-PEG6-amido-bis-PEG5-N3 is employed in the modification of surfaces to improve biocompatibility and prevent non-specific binding. By coating medical devices, biosensors, or nanoparticles with this polymer, researchers can reduce protein adsorption and cell adhesion. This is crucial in improving the performance and longevity of biomedical implants and diagnostics.
Advanced Research Tools: In cutting-edge research, Amino-PEG6-amido-bis-PEG5-N3 is used in the design of multifunctional nanomaterials for various applications, including imaging and targeted therapy. The molecule's functional groups allow for the attachment of multiple agents, such as imaging probes and therapeutic drugs, on a single nanocarrier. This enables the development of theranostic platforms that can diagnose and treat diseases simultaneously.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
