BCN-endo-PEG7-NH2 - CAS 2143968-34-5

BCN-endo-PEG7-NH2 - CAS 2143968-34-5 Catalog number: BADC-01841

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BCN-endo-PEG7-NH2 is an ADC linker containing 7 PEG units.

Category
ADCs Linker
Product Name
BCN-endo-PEG7-NH2
CAS
2143968-34-5
Catalog Number
BADC-01841
Molecular Formula
C27H48N2O9
Molecular Weight
544.68

Ordering Information

Catalog Number Size Price Quantity
BADC-01841 -- $--
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Description
BCN-endo-PEG7-NH2 is an ADC linker containing 7 PEG units.
Synonyms
BCN-exo-PEG7-NH2
IUPAC Name
[(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Canonical SMILES
C1CC2C(C2COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCN)CCC#C1
InChI
InChI=1S/C27H48N2O9/c28-7-9-31-11-13-33-15-17-35-19-21-37-22-20-36-18-16-34-14-12-32-10-8-29-27(30)38-23-26-24-5-3-1-2-4-6-25(24)26/h24-26H,3-23,28H2,(H,29,30)/t24-,25+,26?
InChIKey
WPOFDMZVJSPNSQ-IQCGEYIDSA-N
Density
1.14±0.1 g/cm3
Boiling Point
640.2±55.0 °C at 760 mmHg

BCN-endo-PEG7-NH2, a versatile bifunctional reagent, finds extensive use in bioconjugation and biomedical research. Explore its diverse applications with high perplexity and burstiness:

Protein Labeling: Delve into the world of protein labeling with BCN-endo-PEG7-NH2, a key element for efficiently tagging proteins with imaging agents or therapeutic drugs. Through innovative bioconjugation techniques like click chemistry, researchers can precisely attach BCN-endo-PEG7-NH2 to targeted sites on proteins, all while preserving their functionality. This application is pivotal for investigating dynamic protein behaviors, localization patterns, and intricate interactions within live cellular environments.

Drug Delivery: Unleash the potential of BCN-endo-PEG7-NH2 in crafting tailored drug delivery systems tailored to target specific cells. By conjugating BCN-endo-PEG7-NH2 with both drug molecules and targeting ligands, researchers can steer therapeutic substances directly towards diseased cells, amplifying treatment effectiveness and curtailing off-target impacts.

Nanoparticle Surface Modification: Witness the transformative role of BCN-endo-PEG7-NH2 in enhancing the surface functionalities of nanoparticles, boosting their biocompatibility and targeting precision. Through the incorporation of a polyethylene glycol (PEG) linker, BCN-endo-PEG7-NH2 provides steric hindrance, reducing unwanted protein adsorption and prolonging nanoparticles’ circulation time in the body.

Biosensor Development: Embark on the journey of biosensor innovation with BCN-endo-PEG7-NH2 as a key component for immobilizing essential biomolecules like antibodies and enzymes onto sensor platforms. The robust attachment facilitated by BCN-endo-PEG7-NH2 ensures the sustained activity of biomolecules, elevating the sensitivity and specificity of biosensors. This application assumes critical importance in advancing diagnostic tools and monitoring environmental or clinical samples, shaping the future of biosensor technology.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: BCN-endo-PEG7-NH2
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