BCN-PEG4-HyNic - CAS 1507370-54-8

BCN-PEG4-HyNic - CAS 1507370-54-8 Catalog number: BADC-00959

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Category
ADCs Linker
Product Name
BCN-PEG4-HyNic
CAS
1507370-54-8
Catalog Number
BADC-00959
Molecular Formula
C28H41N5O6
Molecular Weight
543.66

Ordering Information

Catalog Number Size Price Quantity
BADC-00959 -- $--
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Synonyms
5,8-Dioxa-2,11-diazadodecanoic acid, 12-[6-[2-(1-methylethylidene)hydrazinyl]-3-pyridinyl]-12-oxo-, (1alpha,8alpha,9alpha)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
Canonical SMILES
CC(=NNC1=NC=C(C=C1)C(=O)NCCOCCOCCNC(=O)OCC2C3C2CCC#CCC3)C
InChI
InChI=1S/C26H37N5O5/c1-19(2)30-31-24-10-9-20(17-29-24)25(32)27-11-13-34-15-16-35-14-12-28-26(33)36-18-23-21-7-5-3-4-6-8-22(21)23/h9-10,17,21-23H,5-8,11-16,18H2,1-2H3,(H,27,32)(H,28,33)(H,29,31)/t21-,22+,23?
InChIKey
WUZIJQCMBXWWON-AIZNXBIQSA-N
Solubility
10 mm in DMSO
Purity
>98.0%
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.

BCN-PEG4-HyNic, a versatile bifunctional crosslinker, is a powerhouse in both biochemical and medical research due to its exceptional ability to conjugate biomolecules. Explore the multifaceted applications of BCN-PEG4-HyNic showcased with heightened perplexity and burstiness:

Antibody-Drug Conjugates (ADCs): Spearheading advancements in cancer therapy, BCN-PEG4-HyNic plays a pivotal role in synthesizing antibody-drug conjugates. By linking therapeutic antibodies with cytotoxic drugs, this crosslinker facilitates targeted drug delivery to cancerous cells, minimizing off-target effects.

Protein-Protein Interactions: Exploring the intricate world of protein interactions, BCN-PEG4-HyNic emerges as an essential tool for covalently binding a diverse range of proteins. This crosslinking mechanism stabilizes transient protein complexes, enabling in-depth exploration of interaction dynamics and functional analyses.

Diagnostic Assays: Driving the advancement of cutting-edge diagnostic assays like immunoassays and biosensors, BCN-PEG4-HyNic enhances the precision of biomolecule attachment to surfaces or beads. This precision heightens the sensitivity and specificity of disease detection, laying the groundwork for accurate diagnosis and monitoring practices crucial for effective healthcare interventions.

Drug Delivery Systems: Step into the realm of personalized medicine with BCN-PEG4-HyNic as the linchpin in crafting sophisticated drug delivery systems tailored for disease-specific treatments. By bridging drugs with targeting moieties such as ligands or antibodies, this crosslinker orchestrates precise drug delivery, enhancing therapeutic efficacy while reducing systemic toxicity.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: BCN-PEG4-HyNic | Azido-PEG9-acid
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