BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units.
Catalog Number | Size | Price | Quantity | ||
---|---|---|---|---|---|
BADC-00415 | 50 mg | $629 | Inquiry |
BCN-PEG4-NHS ester, a versatile bifunctional crosslinking reagent, plays a pivotal role in bioconjugation and chemical biology. Explore its diverse applications presented with a high degree of perplexity and burstiness:
Protein Labeling: An indispensable tool for scientists, BCN-PEG4-NHS ester is harnessed for the covalent attachment of fluorescent dyes, enzymes, or other biomolecules to proteins. This strategic modification facilitates in-depth exploration of protein dynamics, localization, and interactions through cutting-edge techniques like fluorescence microscopy. The conjugation with BCN-PEG4-NHS ester not only ensures the preservation of biological activity but also enhances the solubility of the labeled proteins, opening new avenues in protein research.
Drug Delivery Systems: Enter the realm of targeted drug delivery systems empowered by BCN-PEG4-NHS ester. By conjugating drugs with specific targeting ligands, such as antibodies or peptides, using this versatile reagent, researchers orchestrate precise delivery of therapeutic agents to designated cells or tissues. This tailored approach not only amplifies the drug’s efficacy but also mitigates off-target effects.
Surface Modification: Witness the transformative power of BCN-PEG4-NHS ester in surface functionalization of nanoparticles, biomaterials, and sensors. The innate chemical groups of this reagent facilitate seamless covalent attachment of biomolecules, elevating the biocompatibility and functionality of the modified surfaces. This pivotal role is instrumental in crafting cutting-edge biosensors, medical implants, and diagnostic devices that boast enhanced performance and reliability.
Click Chemistry: Step into the realm of bio-orthogonal ‘click’ chemistry reactions, where BCN-PEG4-NHS ester shines as a key player. Its efficient reactivity with azide-functionalized molecules forms stable triazole linkages, enabling the assembly of intricate bioconjugates under mild conditions. This innovative application holds immense value in constructing multifunctional biomolecules tailored for research endeavors and therapeutic interventions, propelling scientific discovery and medical advancements to new heights.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.