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Boc-Dil is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01502 | -- | $-- |
Boc-Dil, a widely used protected lysine derivative in peptide synthesis, finds diverse applications with high perplexity and burstiness conveyed through the following key uses:
Peptide Synthesis: Integral to solid-phase peptide synthesis (SPPS), Boc-Dil plays a crucial role in crafting peptides and proteins. The Boc (tert-butyloxycarbonyl) group shields the amino group of lysine, safeguarding it against undesired side reactions during synthesis. After the peptide chain construction, the Boc group can be selectively removed under acidic conditions, yielding the final desired peptide product.
Pharmaceutical Research: Positioned at the forefront of pharmaceutical innovation, Boc-Dil emerges as a key component in the development of peptide-based drugs designed to target specific diseases. Peptides synthesized using Boc-Dil serve as therapeutic agents, enzyme inhibitors, and diagnostic tools. The flexibility of Boc-Dil allows for the production of high-purity peptides essential for clinical applications, highlighting its wide-ranging applications in drug development.
Bioconjugation: In the realm of bioconjugation techniques, Boc-Dil plays a pivotal role in linking peptides or proteins to other molecules for diverse biotechnological applications. The lysine residue, with the protective Boc group, enables selective reactions at designated sites, facilitating the creation of antibody-drug conjugates, peptide-functionalized surfaces, and advanced diagnostics. This strategic use of Boc-Dil showcases its versatility and effectiveness in biotechnology applications.
Structural Biology: Within the field of structural biology, Boc-Dil is harnessed to produce tailor-made peptides that act as invaluable models for studying protein structure and function. These custom peptides mimic specific regions of proteins, offering insights into protein folding, interactions, and biochemical properties. Serving as indispensable tools for deciphering complex biological processes at the molecular level, these model peptides underscore the significance of Boc-Dil in enabling cutting-edge structural biology research.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
