Boc-L-Tyr(PEG(3)-N3)-OH - CAS 1831059-64-3

Boc-L-Tyr(PEG(3)-N3)-OH - CAS 1831059-64-3 Catalog number: BADC-01849

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Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry reagent containing an azide group.

Category
ADCs Linker
Product Name
Boc-L-Tyr(PEG(3)-N3)-OH
CAS
1831059-64-3
Catalog Number
BADC-01849
Molecular Formula
C20H30N4O7
Molecular Weight
438.47

Ordering Information

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Description
Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry reagent containing an azide group.
IUPAC Name
(2S)-3-[4-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)OCCOCCOCCN=[N+]=[N-])C(=O)O
InChI
InChI=1S/C20H30N4O7/c1-20(2,3)31-19(27)23-17(18(25)26)14-15-4-6-16(7-5-15)30-13-12-29-11-10-28-9-8-22-24-21/h4-7,17H,8-14H2,1-3H3,(H,23,27)(H,25,26)/t17-/m0/s1
InChIKey
AUSAOIRHJVEPQZ-KRWDZBQOSA-N

Boc-L-Tyr(PEG(3)-N3)-OH is a chemical compound used in the development of advanced biomedical and biochemical applications. Here are some key applications of Boc-L-Tyr(PEG(3)-N3)-OH:

Biomedical Research: Boc-L-Tyr(PEG(3)-N3)-OH is utilized in the development of drug delivery systems, where its PEG moiety imparts increased solubility and biocompatibility. This compound can be conjugated to therapeutic agents, enhancing their targeted delivery to specific tissues or cells. Researchers often employ it in designing new treatments for cancers and chronic diseases.

Protein Engineering: In protein engineering, Boc-L-Tyr(PEG(3)-N3)-OH is used for site-specific modifications of proteins and peptides. The azide group allows for selective conjugation via click chemistry, enabling the attachment of various functional groups or probes. This facilitates the development of protein-based therapeutics and diagnostics with enhanced properties.

Immunoassays: Boc-L-Tyr(PEG(3)-N3)-OH is valuable in the creation of highly specific and sensitive immunoassays. Its PEG linker can help reduce nonspecific binding and increase the stability of assay components. By conjugating this compound to antibodies or antigens, more accurate and reliable diagnostic tests can be developed.

Surface Modification: Boc-L-Tyr(PEG(3)-N3)-OH is used in surface modification of biomaterials to improve biocompatibility and functionality. The PEG segment provides a hydrophilic layer that reduces protein adsorption and cell adhesion, making it ideal for medical implants and devices. This modification enhances the longevity and performance of medical implants.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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