DBCO-NH-PEG4-maleimide - CAS 1480516-75-3
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DBCO-NH-PEG4-maleimide - CAS 1480516-75-3 Catalog number: BADC-00956

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Category
ADCs Linker
Product Name
DBCO-NH-PEG4-maleimide
CAS
1480516-75-3
Catalog Number
BADC-00956
Molecular Formula
C36H42N4O9
Molecular Weight
674.74
DBCO-NH-PEG4-maleimide

Ordering Information

Catalog Number Size Price Quantity
BADC-00956 -- $--
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Synonyms
DBCO-PEG4-Maleimide;DBCO-NH-PEG4-Maleimide; DBCO-PEG4-MAL
IUPAC Name
N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
Canonical SMILES
C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O
InChI
InChI=1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)
InChIKey
VVFZXPZWVJMYPX-UHFFFAOYSA-N
Density
1.3±0.1 g/cm3
Solubility
10 mm in DMSO
Flash Point
537.6±34.3 °C
Index Of Refraction
1.616
LogP
1.22
Vapor Pressure
0.0±0.3 mmHg at 25°C
Biological Activity
DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Solid
Purity
>98.0%
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
965.2±65.0 °C at 760 mmHg
Form
Solid
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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