Fmoc-Dap-OH - CAS 863971-41-9

Fmoc-Dap-OH - CAS 863971-41-9 Catalog number: BADC-01571

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Fmoc-Dap-OH is an important compound in the field of biomedicine and plays an indispensable role in the complex process of synthesizing various drugs and peptides. This compound is particularly prized for its unique efficacy against infectious diseases and cancer,and has become the cornerstone of the invention of cutting-edge therapies aimed at fighting drug-resistant pathogens or preventing the proliferation of malignant tumors.

Category
ADCs Linker
Product Name
Fmoc-Dap-OH
CAS
863971-41-9
Catalog Number
BADC-01571
Molecular Formula
C24H27NO5
Molecular Weight
409.47
Fmoc-Dap-OH

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Catalog Number Size Price Quantity
BADC-01571 -- $--
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Description
Fmoc-Dap-OH is an important compound in the field of biomedicine and plays an indispensable role in the complex process of synthesizing various drugs and peptides. This compound is particularly prized for its unique efficacy against infectious diseases and cancer,and has become the cornerstone of the invention of cutting-edge therapies aimed at fighting drug-resistant pathogens or preventing the proliferation of malignant tumors.
Synonyms
(2R,3R)-3-[(S)-1-Fmoc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoic Acid
IUPAC Name
3-[1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidin-2-yl]-3-methoxy-2-methylpropanoic acid
Canonical SMILES
CC(C(C1CCCN1C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)OC)C(=O)O
InChI
InChI=1S/C24H27NO5/c1-15(23(26)27)22(29-2)21-12-7-13-25(21)24(28)30-14-20-18-10-5-3-8-16(18)17-9-4-6-11-19(17)20/h3-6,8-11,15,20-22H,7,12-14H2,1-2H3,(H,26,27)
InChIKey
PRTOFBNKUJDFQR-UHFFFAOYSA-N

Fmoc-Dap-OH, a derivative of the amino acid diaminopropionic acid, plays a pivotal role in peptide synthesis and related bioscience applications. Here are four key applications:

Peptide Synthesis: Widely employed in the solid-phase synthesis of peptides, Fmoc-Dap-OH boasts protected amino groups that facilitate the intricate assembly of complex peptide chains. This compound is indispensable for the creation of peptides utilized in a myriad of domains, including research, therapeutic development, and diagnostics.

Antimicrobial Peptide Design: Delving into the realm of antimicrobial peptide design, Fmoc-Dap-OH emerges as a potent asset. By incorporating Fmoc-Dap-OH, researchers can craft antimicrobial peptides with heightened activity, enhanced binding properties, and heightened resistance to enzymatic degradation. These engineered peptides hold promise as potential therapeutics against bacterial infections, offering a new frontier in combating microbial threats.

Protein-Protein Interaction Studies: Unveiling the mysteries of protein-protein interactions, Fmoc-Dap-OH surfaces as a valuable tool, particularly in cases involving lysine-rich regions. Scientists manipulate peptides with Fmoc-Dap-OH to probe the binding affinities and interactions of proteins within intricate signaling pathways. This endeavor aids in pinpointing potential therapeutic targets, enhancing our understanding of fundamental biological processes.

Drug Delivery Systems: Introducing Fmoc-Dap-OH into the realm of drug delivery systems heralds a new era of stability and precision in targeting therapeutic peptides. By incorporating Fmoc-Dap-OH-modified peptides, researchers can enhance the delivery of drugs to specific tissues or cells, thereby elevating the efficacy and reducing potential side effects of peptide-based therapies. This sophisticated approach holds the potential to revolutionize drug delivery mechanisms.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: KY371 | 12-Azido-dodecanoyl-OSu | Fmoc-Dap-OH
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