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Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00942 | 500 mg | $298 | Inquiry |
Fmoc-Val-Ala-PAB-OH, a synthetic peptide prominent in biochemical and pharmaceutical research, finds diverse applications across various fields.
Peptide Synthesis: Acting as a fundamental building block in peptide synthesis, Fmoc-Val-Ala-PAB-OH facilitates the construction of intricate peptide chains through solid-phase techniques. The inclusion of its Fmoc (9-fluorenylmethyloxycarbonyl) group enables sequential peptide assembly, ensuring the production of highly pure peptides essential for a myriad of research and therapeutic endeavors.
Drug Development: In the realm of pharmaceutical innovation, Fmoc-Val-Ala-PAB-OH plays a pivotal role in the design and synthesis of peptide-based drug candidates. These peptides, capable of mimicking natural biological molecules, target specific physiological pathways, with researchers customizing peptide sequences and structures to enhance therapeutic efficacy and safety profiles.
Protease Substrate: Serving as a vital substrate for investigating protease activity, Fmoc-Val-Ala-PAB-OH allows researchers to delve into the specificity and kinetic properties of proteases, pivotal players in a myriad of biological processes. Through such studies, researchers unearth potential protease inhibitors or activators crucial in combatting diseases like cancer and inflammatory disorders, a testament to the peptide’s versatility in biomedical research.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
