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m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01126 | -- | $-- | Inquiry |
m-PEG7-Ms, also known as methoxy-polyethylene glycol methylsulfonate, is a versatile compound widely embraced in the biosciences for its remarkable capabilities in modifying and enhancing biological molecules. Here are four key applications of m-PEG7-Ms:
Protein PEGylation: Embracing m-PEG7-Ms in the realm of protein PEGylation, scientists engage in a meticulous process of affixing polyethylene glycol chains to protein molecules. This transformative modification elevates the stability and solubility of proteins, diminishing their immunogenicity while elongating their half-life in the bloodstream. Consequently, PEGylated proteins emerge as favorable candidates in therapeutic realms, especially within drug delivery systems, offering enhanced treatment options.
Drug Delivery Systems: Within the intricate domain of drug delivery, m-PEG7-Ms serves as a pivotal linker, bridging drugs with polymers to amplify their therapeutic potency and bioavailability. By enveloping the drug with a protective hydrophilic shield, m-PEG7-Ms minimizes degradation and swift clearance rates, paving the path for controlled drug release and precise targeted delivery.
Nanoparticle Functionalization: Delving into the domain of nanoparticle functionalization, m-PEG7-Ms emerges as a game-changer, enhancing biocompatibility and stability. Through the strategic modification of nanoparticle surfaces with PEG chains, these particles attain a stealth-like characteristic, evading immune system recognition and clearance.
Surface Coating in Biosensors: In the realm of biosensors, m-PEG7-Ms takes center stage, offering a shield against non-specific binding and fouling that could compromise sensor performance. The inherent hydrophilic nature of PEG preserves the bioactivity of sensors while extending their functional lifespan. This critical application plays a pivotal role in elevating the sensitivity and accuracy of biosensors utilized in crucial domains such as clinical diagnostics and environmental monitoring.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
