m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Catalog Number | Size | Price | Quantity | |
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BADC-00884 | -- | $-- | Inquiry |
m-PEG8-Ms, a polyethylene glycol derivative widely utilized in biochemical and pharmaceutical realms, finds diverse applications.
Drug Delivery Systems: In the realm of drug delivery, m-PEG8-Ms plays a pivotal role in enhancing the solubility and stability of pharmaceuticals. By conjugating polyethylene glycol chains to drug molecules, it elevates their bioavailability and extends their circulation time within the bloodstream.
Protein Conjugation: Within the domain of protein chemistry, m-PEG8-Ms is a cornerstone for pegylation, a process involving the attachment of PEG moieties to proteins. This innovative procedure serves to diminish immunogenicity and prolong the half-life of therapeutic proteins and peptides.
Biocompatible Coatings: Leveraging the hydrophilic properties of PEG, m-PEG8-Ms finds application in forming biocompatible coatings on medical devices and implants. These coatings effectively mitigate protein adsorption and cell adhesion, thereby reducing the risk of immune responses and infections.
Nanoparticle Functionalization: For the functionalization of nanoparticles in diagnostic and therapeutic applications, m-PEG8-Ms emerges as a crucial player. By modifying nanoparticle surfaces with PEG chains, it enhances their stability and biocompatibility in biological settings, leading to the creation of nanoformulations tailored for targeted drug delivery and cutting-edge imaging technologies.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.