MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH - CAS 1802520-40-6
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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH - CAS 1802520-40-6 Catalog number: BADC-01722

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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
CAS
1802520-40-6
Catalog Number
BADC-01722
Molecular Formula
C28H36N6O10
Molecular Weight
616.62

Ordering Information

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Description
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
(R)-10-Benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid
IUPAC Name
2-[[[2-[[(2R)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]methoxy]acetic acid
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)NCC(=O)NCOCC(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O
InChI
InChI=1S/C28H36N6O10/c35-21(9-5-2-6-12-34-25(39)10-11-26(34)40)29-14-22(36)30-16-24(38)33-20(13-19-7-3-1-4-8-19)28(43)31-15-23(37)32-18-44-17-27(41)42/h1,3-4,7-8,10-11,20H,2,5-6,9,12-18H2,(H,29,35)(H,30,36)(H,31,43)(H,32,37)(H,33,38)(H,41,42)/t20-/m1/s1
InChIKey
SODPQQOBNODMSG-HXUWFJFHSA-N
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Historical Records: MMAF-OMe | N3-D-Orn(Boc)-OH | MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
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