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MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for the synthesis of anti-human EGFR antibody agent conjugate.
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01746 | -- | $-- | Inquiry |
MC-Gly-Gly-Phe-Gly-PAB-PNP, a versatile synthetic peptide substrate utilized in biochemical and pharmacological research across various disciplines, stands as a cornerstone in numerous applications.
Enzyme Activity Assays: Positioned at the forefront of enzyme research, MC-Gly-Gly-Phe-Gly-PAB-PNP assumes a crucial role in investigating protease activity, particularly those targeting glycine-phenylalanine sequences. Upon enzymatic cleavage, this substrate releases a detectable product or chromophore, enabling precise quantification of enzyme kinetics.
Drug Screening: Within the sphere of pharmacology, MC-Gly-Gly-Phe-Gly-PAB-PNP emerges as a pivotal component for high-throughput evaluation of drug candidates designed to modulate protease activities. By furnishing researchers with a consistent and reliable substrate, this peptide facilitates the assessment of novel compounds in influencing protease behavior. This platform plays a critical role in discovering and refining therapeutic modalities targeting abnormal protease function in diseases such as cancer and neurodegeneration.
Biochemical Pathway Analysis: Delving into the intricate realm of biochemical pathways, MC-Gly-Gly-Phe-Gly-PAB-PNP acts as a guiding light for investigating proteolytic mechanisms. By analyzing cleavage patterns of the substrate, scientists unlock vital insights into the functions of specific proteases and their interactions within complex biological environments. This knowledge forms the bedrock for unraveling cellular processes and developing strategies to manipulate metabolic and signaling pathways with precision.
Diagnostic Tool Development: In the domain of medical diagnostics, MC-Gly-Gly-Phe-Gly-PAB-PNP emerges as a cornerstone for creating diagnostic assays aimed at detecting altered protease activity in clinical specimens. These assays play a crucial role in diagnosing conditions characterized by abnormal protease behavior, such as certain cancers or inflammatory disorders. By monitoring substrate conversions in patient samples, clinicians extract valuable information essential for disease surveillance and prognosis assessment.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
