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NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00915 | -- | $-- |
Amino-PEG6-t-butyl ester, a versatile compound renowned for its role in bioconjugation and drug delivery, finds diverse applications in the following realms presented with high perplexity and burstiness:
Drug Delivery: The utilization of Amino-PEG6-t-butyl ester transcends conventional drug delivery paradigms by augmenting the solubility and stability of therapeutic agents. Through conjugating this compound with drugs, the potential arises to elevate their bioavailability and mitigate immunogenic responses. This innovative approach holds the promise of rendering treatments more efficacious while mitigating undesirable side effects.
Bioconjugation: At the vanguard of bioconjugation, Amino-PEG6-t-butyl ester plays a pivotal role in facilitating the coupling of biomolecules to diverse surfaces and carriers. Leveraging this compound, researchers can affix enzymes, antibodies, or other proteins to nanoparticles or alternative delivery systems. This synergistic union enhances the precision and potency of both diagnostic and therapeutic agents, propelling advancements in personalized medicine.
Surface Modification: Amino-PEG6-t-butyl ester emerges as a linchpin in enhancing the surface characteristics of biomaterials and medical devices. Through coating surfaces with this compound, a myriad of benefits ensue, including reduced fouling, heightened biocompatibility, and enhanced performance of implants and diagnostic tools. This strategic application stands as a cornerstone in prolonging the service life and efficacy of crucial medical devices.
Protein Purification: In the intricate realm of biochemical research, the utility of Amino-PEG6-t-butyl ester shines brightly in the realm of affinity chromatography for protein purification. By affixing this compound to chromatographic resins, scientists can selectively capture and elute target proteins from complex mixtures with precision.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
