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Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01090 | -- | $-- | Inquiry |
Boc-aminooxy-amide-PEG4-propargyl, a versatile chemical linker, plays a pivotal role in advanced biomedical research and drug development. Here are four key applications presented with high perplexity and burstiness:
Chemical Biology: Delving into the realm of chemical biology, Boc-aminooxy-amide-PEG4-propargyl is a cornerstone for synthesizing conjugates and probes. Its reactive moieties allow for precise attachment to functional groups on biomolecules, enabling the exploration of protein interactions and cellular processes. This facilitates the meticulous tracking and manipulation of biological molecules, fueling advancements in live-cell imaging and experimental setups.
Drug Delivery: In the intricate landscape of drug delivery systems, Boc-aminooxy-amide-PEG4-propargyl serves as a pivotal linker to connect therapeutic agents with targeting molecules like antibodies or peptides. This fusion leads to the creation of targeted delivery systems that deliver drugs directly to afflicted cells, minimizing side effects and boosting therapeutic potency. The PEG4 spacer enhances solubility and biocompatibility, rendering this compound versatile for a myriad of delivery platforms.
Bioconjugation: A linchpin in bioconjugation techniques, Boc-aminooxy-amide-PEG4-propargyl acts as a vital reagent in linking biomolecules such as proteins, nucleic acids, or small molecules. This symbiotic connection is essential for crafting diagnostic tools, biosensors, and therapeutic agents. The propargyl group provides a conduit for click chemistry, enabling efficient and selective conjugation under mild conditions, propelling forward the realm of bioconjugation.
Proteomics: Unveiling the mysteries of proteomics research, Boc-aminooxy-amide-PEG4-propargyl plays a pivotal role in modifying and labeling proteins to unravel their structural and functional intricacies. Employed in techniques like mass spectrometry, it aids in identifying protein modifications and interactions. This intricate process aids in the comprehensive analysis of protein networks and the unveiling of crucial biomarkers, shedding light on the intricate dance of proteins within biological systems.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
