Boc-aminooxy-ethyl-SS-propanol - CAS 2128735-21-5

Boc-aminooxy-ethyl-SS-propanol - CAS 2128735-21-5 Catalog number: BADC-01070

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Category
ADCs Linker
Product Name
Boc-aminooxy-ethyl-SS-propanol
CAS
2128735-21-5
Catalog Number
BADC-01070
Molecular Formula
C9H19NO4S2
Molecular Weight
269.38
Purity
>98.0%

Ordering Information

Catalog Number Size Price Quantity
BADC-01070 -- $-- Inquiry
Synonyms
Tert-butyl (2-((2-hydroxyethyl)disulfanyl)ethoxy)carbamate
Canonical SMILES
CC(C)(C)OC(=O)NOCCSSCCO
InChI
InChI=1S/C9H19NO4S2/c1-9(2,3)14-8(12)10-13-5-7-16-15-6-4-11/h11H,4-7H2,1-3H3,(H,10,12)
InChIKey
FJJVBSKVTYVXFL-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

Boc-aminooxy-ethyl-SS-propanol, a versatile reagent used in biochemical research and synthesis, boasts a myriad of applications. Below are four key applications presented with high perplexity and burstiness:

Protein Cross-Linking: Delving into protein stabilization, Boc-aminooxy-ethyl-SS-propanol engages in protein cross-linking reactions. By forging robust oxime bonds with aldehyde groups on proteins, it facilitates the exploration of protein-protein interactions and complex formation, a cornerstone in the realms of structural biology and proteomics.

Peptide Synthesis: As a pivotal player in peptide synthesis, Boc-aminooxy-ethyl-SS-propanol serves as a foundational unit. Its aminooxy group reacts with carbonyl-containing compounds, culminating in stable oxime linkages essential for crafting novel peptide structures. This capability empowers researchers to fashion peptides endowed with heightened stability and functionality, propelling innovation in the field.

Drug Delivery Systems: With an eye on advancing drug delivery systems, Boc-aminooxy-ethyl-SS-propanol comes into play in the creation of prodrugs. These prodrugs, engineered for superior bioavailability and stability of active pharmaceutical ingredients, offer controlled-release mechanisms that amplify therapeutic outcomes. Particularly beneficial for unstable or poorly absorbed drugs, this approach heralds a new era in drug delivery technology.

Chemical Labeling: Tackling the domain of chemical labeling, Boc-aminooxy-ethyl-SS-propanol emerges as an indispensable tool for biomolecule modification. Enabling the attachment of functional groups to biomolecules like proteins and nucleic acids, it facilitates detection, imaging, and further chemical manipulation. This technique is integral to diverse applications, from probing biomolecular interactions to tracking molecules within intricate biological systems, enabling profound insights into the biochemical landscape.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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