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(4S)-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01930 | -- | $-- |
(4S)-4-Hydroxy-L-proline hydrochloride, an amino acid derivative of great importance in biomedical and biochemical research, finds diverse applications. Here are four key applications presented with high perplexity and burstiness://
Collagen Synthesis and Studies: Serving as a fundamental component for collagen synthesis, (4S)-4-Hydroxy-L-proline hydrochloride plays a vital role in building this crucial structural protein within the body. It is a key player in research endeavors aimed at unraveling the intricacies of collagen formation, stability, and its implications in connective tissue disorders. This compound is a cornerstone in the exploration of the intricate biochemical pathways governing collagen biosynthesis and degradation.
Biomarker Development: Utilized as a biomarker in the diagnosis and monitoring of fibrotic ailments and connective tissue disorders, (4S)-4-Hydroxy-L-proline hydrochloride offers valuable insights. Elevated levels of this compound in bodily fluids serve as indicators of skewed collagen turnover, shedding light on conditions like liver fibrosis and scleroderma. Clinical investigations leverage this biomarker to gauge disease progression and evaluate responses to therapeutic interventions.
Cosmetic and Dermatological Research: Embraced by the cosmetic industry, this compound features prominently in the formulation of products designed to enhance skin health and expedite wound healing processes. Through its involvement in collagen generation, (4S)-4-Hydroxy-L-proline hydrochloride is integrated into formulations targeting wrinkle reduction, skin elasticity enhancement, and tissue repair. Dermatological research delves into its usability and potential benefits in topical applications, fueling innovations in skincare.
Pharmaceutical Manufacturing: Enlisted as a pivotal component in the synthesis of various pharmaceuticals, particularly those addressing connective tissue disorders, (4S)-4-Hydroxy-L-proline hydrochloride serves as a precursor or intermediary. Its integration into the pharmaceutical development landscape ensures the efficacy of medications aimed at bolstering collagen repair and maintenance. The compound's esteemed reliability and consistency position it as a coveted ingredient in pharmaceutical formulations, underpinning the advancement of therapeutic solutions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
