(4S)-4-Hydroxy-L-proline hydrochloride - CAS 441067-49-8

(4S)-4-Hydroxy-L-proline hydrochloride - CAS 441067-49-8 Catalog number: BADC-01930

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(4S)-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
(4S)-4-Hydroxy-L-proline hydrochloride
CAS
441067-49-8
Catalog Number
BADC-01930
Molecular Formula
C5H10ClNO3
Molecular Weight
167.59
(4S)-4-Hydroxy-L-proline hydrochloride

Ordering Information

Catalog Number Size Price Quantity
BADC-01930 -- $-- Inquiry
Description
(4S)-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Cis-4-Hydroxy-L-Proline Hydrochloride; (4S)-4-Hydroxy-L-Proline HCl
IUPAC Name
(2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid;hydrochloride
Canonical SMILES
C1C(CNC1C(=O)O)O.Cl
InChI
InChI=1S/C5H9NO3.ClH/c7-3-1-4(5(8)9)6-2-3;/h3-4,6-7H,1-2H2,(H,8,9);1H/t3-,4-;/m0./s1
InChIKey
YEJFFQAGTXBSTI-MMALYQPHSA-N

(4S)-4-Hydroxy-L-proline hydrochloride, an amino acid derivative of great importance in biomedical and biochemical research, finds diverse applications. Here are four key applications presented with high perplexity and burstiness://

Collagen Synthesis and Studies: Serving as a fundamental component for collagen synthesis, (4S)-4-Hydroxy-L-proline hydrochloride plays a vital role in building this crucial structural protein within the body. It is a key player in research endeavors aimed at unraveling the intricacies of collagen formation, stability, and its implications in connective tissue disorders. This compound is a cornerstone in the exploration of the intricate biochemical pathways governing collagen biosynthesis and degradation.

Biomarker Development: Utilized as a biomarker in the diagnosis and monitoring of fibrotic ailments and connective tissue disorders, (4S)-4-Hydroxy-L-proline hydrochloride offers valuable insights. Elevated levels of this compound in bodily fluids serve as indicators of skewed collagen turnover, shedding light on conditions like liver fibrosis and scleroderma. Clinical investigations leverage this biomarker to gauge disease progression and evaluate responses to therapeutic interventions.

Cosmetic and Dermatological Research: Embraced by the cosmetic industry, this compound features prominently in the formulation of products designed to enhance skin health and expedite wound healing processes. Through its involvement in collagen generation, (4S)-4-Hydroxy-L-proline hydrochloride is integrated into formulations targeting wrinkle reduction, skin elasticity enhancement, and tissue repair. Dermatological research delves into its usability and potential benefits in topical applications, fueling innovations in skincare.

Pharmaceutical Manufacturing: Enlisted as a pivotal component in the synthesis of various pharmaceuticals, particularly those addressing connective tissue disorders, (4S)-4-Hydroxy-L-proline hydrochloride serves as a precursor or intermediary. Its integration into the pharmaceutical development landscape ensures the efficacy of medications aimed at bolstering collagen repair and maintenance. The compound's esteemed reliability and consistency position it as a coveted ingredient in pharmaceutical formulations, underpinning the advancement of therapeutic solutions.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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