S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate - CAS 2127875-65-2
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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate - CAS 2127875-65-2 Catalog number: BADC-01069

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Category
ADCs Linker
Product Name
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
CAS
2127875-65-2
Catalog Number
BADC-01069
Molecular Formula
C5H12O3S2
Molecular Weight
184.28
Purity
≥95.0%

Ordering Information

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BADC-01069 -- $-- Inquiry

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Synonyms
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate; 2-methyl-2-methylsulfonylsulfanylpropan-1-ol
Canonical SMILES
CC(C)(CO)SS(=O)(=O)C
InChI
InChI=1S/C5H12O3S2/c1-5(2,4-6)9-10(3,7)8/h6H,4H2,1-3H3
InChIKey
DRRLIMMXMOWDCA-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
-20°C (International: -20°C)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Biological Activity
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1] .
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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