Boc-Gly-Gly-Phe-Gly-OH TFA is a protease cleavable linker used for the antibody-drug conjugates (ADCs).
Catalog Number | Size | Price | Quantity | ||
---|---|---|---|---|---|
BADC-01711 | -- | $-- | Inquiry |
Boc-Gly-Gly-Phe-Gly-OH (TFA) is a protected peptide widely utilized in bioscience research and pharmaceutical manufacturing. Here are four key applications of Boc-Gly-Gly-Phe-Gly-OH (TFA) presented with high perplexity and burstiness:
Peptide Synthesis: Acting as a crucial building block in peptide and protein synthesis, Boc-Gly-Gly-Phe-Gly-OH (TFA) plays a pivotal role. Its Boc protecting group enables selective reactions with other amino acids, preventing premature interactions. This mechanism facilitates the efficient assembly of peptides, ensuring high purity and yield levels.
Drug Development: Within the realm of pharmaceutical exploration, Boc-Gly-Gly-Phe-Gly-OH (TFA) contributes significantly to the creation of peptide-based drug candidates. Researchers leverage this peptide to investigate drug-receptor interactions and assess the therapeutic potential of novel medications. Its well-defined structure positions it as an ideal candidate for conducting structure-activity relationship studies in drug development.
Enzyme Substrate Studies: Frequently utilized as a substrate in enzymatic assays, Boc-Gly-Gly-Phe-Gly-OH (TFA) enables scientists to delve into the activities and specificities of proteolytic enzymes. Through monitoring how enzymes cleave this peptide, valuable insights into enzyme kinetics and mechanisms are garnered. This knowledge serves as a cornerstone for designing enzyme inhibitors and therapeutic interventions.
Structural Biology: In the domain of structural biology, Boc-Gly-Gly-Phe-Gly-OH (TFA) finds application in constructing peptide models for X-ray crystallography and NMR studies. These models aid scientists in deciphering the three-dimensional structures and folding mechanisms of proteins. Accurate structural data is indispensable for rational drug design and unraveling protein functionalities at a molecular level.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.