Boc-Gly-Gly-Phe-OH - CAS 39621-73-3

Boc-Gly-Gly-Phe-OH - CAS 39621-73-3 Catalog number: BADC-01442

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Boc-Gly-Gly-Phe-OH is a biochemical compound widely used in the biomedical industry. It acts as a potent inhibitor, targeting specific enzymes involved in the growth and proliferation of cancer cells. This product demonstrates promising potential in the treatment of various types of cancers by hindering their progression and metastasis.

Category
ADCs Linker
Product Name
Boc-Gly-Gly-Phe-OH
CAS
39621-73-3
Catalog Number
BADC-01442
Molecular Formula
C18H25N3O6
Molecular Weight
379.41
Boc-Gly-Gly-Phe-OH

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Catalog Number Size Price Quantity
BADC-01442 -- $--
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Description
Boc-Gly-Gly-Phe-OH is a biochemical compound widely used in the biomedical industry. It acts as a potent inhibitor, targeting specific enzymes involved in the growth and proliferation of cancer cells. This product demonstrates promising potential in the treatment of various types of cancers by hindering their progression and metastasis.
Synonyms
(tert-Butoxycarbonyl)glycylglycyl-L-phenylalanine; N-(tert-Butoxycarbonyl)glycylglycyl-L-phenylalanine; N-[N-[N-(tertbutoxycarbonyl)glycyl]glycyl]-L-phenylalanine
IUPAC Name
(2S)-2-[[2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
Canonical SMILES
CC(C)(C)OC(=O)NCC(=O)NCC(=O)NC(CC1=CC=CC=C1)C(=O)O
InChI
InChI=1S/C18H25N3O6/c1-18(2,3)27-17(26)20-10-14(22)19-11-15(23)21-13(16(24)25)9-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,19,22)(H,20,26)(H,21,23)(H,24,25)/t13-/m0/s1
InChIKey
ZNKXERAHRITSBL-ZDUSSCGKSA-N
Appearance
White Solid

Boc-Gly-Gly-Phe-OH, a peptide characterized by a protected amino terminus, plays a pivotal role in biochemistry and pharmaceutical research. Below are four key applications of Boc-Gly-Gly-Phe-OH:

Peptide Synthesis: Serving as a fundamental unit in peptide assembly, Boc-Gly-Gly-Phe-OH acts as a cornerstone for constructing larger peptide chains with precise sequences. Researchers harness its stability and facile deprotection in solid-phase peptide synthesis (SPPS) techniques, enabling the extension of peptides with targeted functionalities and structures.

Drug Development: Within the realm of pharmaceutical exploration, Boc-Gly-Gly-Phe-OH emerges as a crucial component in the design and synthesis of peptide-based medications. The inclusion of phenylalanine (Phe) in its composition impacts the bioactivity and ligand-binding characteristics of resultant peptides, facilitating the creation of innovative therapeutics tailored for specific biological targets.

Enzyme Inhibition Studies: Exploiting the versatility of Boc-Gly-Gly-Phe-OH, researchers employ this compound as both a substrate and inhibitor in investigations of enzymatic activity. By probing protease behavior and specificity through observation of cleavage and binding patterns, scientists gain valuable insights into enzyme mechanisms, illuminating potential avenues for therapeutic intervention.

Structural Biology: In the domain of structural biology, Boc-Gly-Gly-Phe-OH assumes a critical role in unraveling protein-peptide interactions. Integrating this peptide into larger protein complexes, researchers utilize techniques such as X-ray crystallography and NMR spectroscopy to elucidate molecular structures, enhancing comprehension of protein conformation and functionality.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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