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| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00910 | -- | $-- |
DBCO-NHCO-PEG4-NH-Boc, a versatile bifunctional reagent utilized in bioconjugation and click chemistry applications, exhibits a wide array of uses. Explore these four key applications:
Protein Labeling: Through the innovative copper-free click chemistry approach, researchers leverage DBCO-NHCO-PEG4-NH-Boc for precise protein labeling with diverse tags or fluorophores. This advanced reagent enables efficient and specific conjugation under mild conditions, preserving protein functionality. Scientists employ this method to delve into protein interactions and dynamics within living cells.
Drug Delivery Systems: In the domain of drug delivery research, DBCO-NHCO-PEG4-NH-Boc serves as a vital tool for linking therapeutic agents to targeted moieties like antibodies or peptides. This conjugation strategy enhances the specificity of drug delivery to intended cells or tissues, minimizing side effects and maximizing therapeutic effectiveness. The inclusion of the flexible PEG4 linker mitigates potential steric hindrance, optimizing drug delivery precision.
Biomaterial Functionalization: Embracing biomaterial innovation, DBCO-NHCO-PEG4-NH-Boc empowers the functionalization of biomaterials such as hydrogels or nanoparticles with bioactive compounds. This process facilitates the creation of advanced materials tailored for specific properties crucial in tissue engineering or diagnostic applications. The utilization of this reagent enables precise and stable modifications, essential for crafting responsive biomaterials that push the boundaries of material science.
Diagnostic Assays: In the realm of diagnostic assay development, DBCO-NHCO-PEG4-NH-Boc plays a pivotal role in attaching detection probes to antibodies or other binding molecules. This modification enables the sensitive and specific detection of target analytes across various sample matrices. The integration of click chemistry expedites the conjugation process, enhancing assay performance and reliability.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
