Inquiry Basket
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00883 | -- | $-- | Inquiry |
mPEG7-aldehyde, a derivative of polyethylene glycol featuring a reactive aldehyde group, is a versatile tool with wide-reaching applications in bioconjugation and drug delivery.
Bioconjugation: Harnessing the exceptional attributes of mPEG7-aldehyde, researchers skillfully alter proteins, peptides, and antibodies through covalent attachment, enhancing their stability and solubility. The aldehyde group selectively interacts with amine groups on biomolecules, leading to the formation of robust Schiff base linkages. This application plays a pivotal role in crafting conjugate vaccines, targeted therapeutics, and cutting-edge diagnostic agents.
Drug Delivery: Within drug delivery systems, mPEG7-aldehyde serves as a cornerstone in developing PEGylated drugs with improved pharmacokinetics and reduced immunogenicity. Through strategic attachment to the drug molecule, researchers prolong its circulation time and enhance its bioavailability. This innovative approach holds promise in boosting the effectiveness of therapeutic proteins and peptides.
Surface Modification: Emerging as a key player in biomaterials and medical devices, mPEG7-aldehyde plays a crucial role in surface modification, enhancing biocompatibility and preventing protein adsorption. The aldehyde functionality enables seamless bonding to various substrates, facilitating the creation of antifouling surfaces essential for biosensors and implantable devices.
Nanotechnology: In the dynamic realm of nanotechnology, mPEG7-aldehyde assumes a pivotal role as a stabilizing agent for nanoparticles utilized in diagnostics and therapeutics. By enveloping nanoparticles with mPEG7-aldehyde, their stability and dispersion in biological environments are significantly improved. This cutting-edge application is instrumental in enhancing the precision of targeting and efficiency of delivery in nanoparticle-based drug formulations and advanced imaging agents, propelling the boundaries of precision medicine and molecular imaging.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
