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m-PEG7-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00904 | -- | $-- | Inquiry |
m-PEG7-CH2CH2CHO, a small molecule frequently employed as a functional linker in diverse bioscience and pharmaceutical settings, finds utility in various applications.
Drug Delivery Systems: Within drug conjugation processes, m-PEG7-CH2CH2CHO plays a pivotal role in enhancing the solubility and stability of therapeutic agents. Serving as a critical linker, it facilitates the attachment of drugs to polymers, thereby augmenting their circulation time and bioavailability. This structural modification is indispensable for crafting more efficacious drug delivery systems capable of targeting specific tissues or cells with precision.
Bioconjugation: At the intersection of chemistry and biology, m-PEG7-CH2CH2CHO finds application in bioconjugation to alter proteins, antibodies, and other biomolecules. Leveraging the aldehyde group within m-PEG7-CH2CH2CHO, stable linkages can be forged with amines on biomolecules, enabling site-specific labeling or immobilization.
Surface Modification: In the domain of biotechnology and medical devices, m-PEG7-CH2CH2CHO serves as a key player in surface modification processes. By engaging with substrates, it imparts non-fouling and hydrophilic characteristics to surfaces, effectively curtailing protein adsorption and cell adhesion. This attribute proves advantageous in the creation of biocompatible surfaces ideal for implants and sensor technologies.
Nanoparticle Functionalization: In the world of nanotechnology, m-PEG7-CH2CH2CHO assumes a crucial role in the functionalization of nanoparticles, heightening their biocompatibility and stability within biological environments. Harnessing its PEG moiety, it bestows a stealth effect upon nanoparticles, diminishing immunogenicity and prolonging their circulation within the body. This advancement lays the foundation for the successful development of nanoparticles tailored for precise drug delivery and imaging applications, pushing forward the frontier of nanomedicine.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
