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Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00922 | -- | $-- |
Bis-PEG2-PFP ester, a chemical compound commonly employed in bioconjugation and surface modifications, finds diverse applications in various biochemistry fields. Here are four key applications presented with a high degree of perplexity and burstiness:
Protein Crosslinking: At the forefront of bioconjugation, Bis-PEG2-PFP ester plays a pivotal role in protein crosslinking processes. By engaging with amine groups on proteins, it establishes stable covalent bonds, enabling the formation of intricate protein complexes. This technique proves invaluable for the synthesis of antibody-drug conjugates and the exploration of protein-protein interactions, shedding light on intricate molecular relationships within biological systems.
Surface Modification: Delving into surface modification, Bis-PEG2-PFP ester serves as a versatile tool for functionalizing various biomedical surfaces and nanoparticles. Through conjugation with biomolecules, it elevates the biocompatibility and specificity of diagnostic and therapeutic surfaces, enhancing their overall performance. This precision engineering reduces the risk of immune reactions in medical devices and drug delivery systems, thus bolstering the safety and efficacy of biomedical technologies.
Development of Drug Delivery Systems: In the realm of drug delivery, Bis-PEG2-PFP ester emerges as a crucial component in enhancing the solubility and stability of drug molecules. This process of PEGylation, facilitated by Bis-PEG2-PFP ester, prolongs drug circulation in the bloodstream, amplifying therapeutic outcomes. The compound’s role in crafting sustained-release formulations and targeted drug delivery systems underscores its significance in advancing pharmaceutical technologies, ultimately improving patient care and treatment efficacy.
Creating Bioconjugates: Finally, Bis-PEG2-PFP ester enables the customization of bioconjugates for a myriad of biochemical assays, pushing the boundaries of diagnostic tools and biosensing applications. By linking enzymes, antibodies, or other biomolecules to detection tags, it empowers the development of sensitive and specific diagnostic platforms critical for medical diagnostics and analytical applications. This intricate interplay of molecules in bioconjugates opens new vistas in the realm of biochemistry, offering novel insights and applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
