Bis-PEG7-NHS ester is a non-cleavable 7-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Catalog Number | Size | Price | Quantity |
---|---|---|---|
BADC-00924 | -- | $-- |
Bis-PEG7-NHS ester is a crosslinking reagent widely used in bioconjugation and chemical biology. Here are some key applications of Bis-PEG7-NHS ester:
Protein-Protein Conjugation: Bis-PEG7-NHS ester is commonly used to link two proteins together, forming stable protein-protein conjugates. This technique is essential for creating bifunctional proteins for research and therapeutic purposes. It allows for the study of protein interactions and the development of multi-functional biotherapeutics.
Antibody-Drug Conjugates (ADCs): In the development of targeted cancer therapies, Bis-PEG7-NHS ester is used to attach cytotoxic drugs to antibodies. By forming a stable linker between the drug and the antibody, it ensures targeted delivery of the drug to cancer cells, minimizing off-target effects. This technology is pivotal for enhancing the efficacy and specificity of cancer treatments.
Surface Modification: Bis-PEG7-NHS ester is utilized to modify surfaces of various materials, such as nanoparticles, glass, and polymers. By attaching functional groups to surfaces, it enhances biocompatibility, reduces non-specific binding, and improves the stability of biomedical devices. This application is critical for the development of biosensors, implants, and diagnostic tools.
Peptide Synthesis: In peptide synthesis, Bis-PEG7-NHS ester is employed to link peptides together or to attach peptides to other molecules. This crosslinking is crucial for creating peptide arrays, peptide-based drugs, and for studying peptide interactions. It enables the design of complex peptide structures with improved stability and functionality.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.