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Bis-PEG6-NHS ester is a non-cleavable 6-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00960 | -- | $-- |
Bis-PEG6-NHS ester, a versatile bifunctional reagent, finds extensive use in bioconjugation and drug delivery applications owing to its unique ability to connect biomolecules. Here are four key applications of Bis-PEG6-NHS ester delivered with a high degree of perplexity and burstiness:
Drug Delivery Systems: Positioned at the forefront of drug delivery innovation, Bis-PEG6-NHS ester plays a pivotal role in crafting drug delivery systems. It acts as a crucial bridge linking therapeutic agents to carrier molecules like nanoparticles or proteins, thereby enhancing drug solubility, stability, and bioavailability. This enables targeted and sustained release of therapeutics, ultimately elevating treatment efficacy while mitigating undesirable side effects.
Protein Crosslinking: Within the realm of protein chemistry, Bis-PEG6-NHS ester serves as a cornerstone for crosslinking proteins, facilitating the exploration of intricate protein-protein interactions and the stabilization of protein complexes. By establishing robust covalent bonds between amino groups of lysine residues on diverse proteins, researchers delve into the structural and functional dimensions of complex biological systems, shedding light on fundamental cellular processes and protein functionality.
Immunoassays Development: In the arena of immunoassays development, Bis-PEG6-NHS ester emerges as a valuable asset employed to conjugate antibodies to detection enzymes or fluorophores. This strategic coupling enhances the sensitivity and specificity of diagnostic assays, crucial for both diagnostics and research. Improved signal detection mechanisms enable precise quantification of biomarkers and analytes in a myriad of samples, catapulting the accuracy of immunoassay outcomes to new heights.
Surface Functionalization: Embarking on a journey into biomaterial science, Bis-PEG6-NHS ester takes center stage in surface functionalization processes aimed at enhancing medical devices and biosensors. By tethering bioactive molecules to these surfaces, it elevates the biocompatibility and functionality of implants, diagnostic tools, and tissue engineering scaffolds. This pivotal role contributes to enhanced patient outcomes and propels advancements in medical device technology to newer horizons.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
