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Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01204 | -- | $-- |
Ald-Ph-PEG4-bis-PEG4-propargyl is a multifunctional compound used widely in bioconjugation and drug delivery systems. Here are some key applications of Ald-Ph-PEG4-bis-PEG4-propargyl:
Drug Delivery: Ald-Ph-PEG4-bis-PEG4-propargyl is utilized in the design of advanced drug delivery systems. Its bifunctional nature allows for the attachment of therapeutic agents to targeting moieties, enhancing the specific delivery of drugs to designated tissues. This can improve the efficacy and reduce the side effects of medications.
Bioconjugation: This compound is frequently employed in bioconjugation protocols to link biomolecules, such as proteins and antibodies, with various tags and probes. The alkyne group readily reacts with azides via click chemistry, facilitating the creation of stable bioconjugates. These conjugates are instrumental in diagnostic assays and therapeutic developments.
Imaging: Ald-Ph-PEG4-bis-PEG4-propargyl can be used to prepare imaging agents for both in vitro and in vivo applications. By conjugating imaging probes, such as fluorescent dyes or radioactive isotopes, researchers can visualize and track biological processes with high specificity. This aids in disease diagnosis and monitoring of treatment progress.
Surface Functionalization: In materials science, this compound is used for surface functionalization of nanoparticles and other substrates. It allows for the attachment of various functional groups to the surface, which can be utilized for targeting, sensing, and catalysis applications. This functionalization enhances the material's properties for use in biomedical devices and environmental sensors.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
