Catalog Number | Size | Price | Quantity | ||
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BADC-00591 | -- | $-- | Inquiry |
DBCO-NHS ester 3, a click chemistry reagent widely embraced in biosciences, presents diverse avenues for biomolecule conjugation. Here are four key applications:
Bioconjugation: Harnessing the power of DBCO-NHS ester 3 in bioconjugation techniques links proteins, peptides, or other biomolecules with azide-functionalized counterparts, ushering in the era of antibody-drug conjugates, nanoparticles, and biosensors. These conjugates serve as linchpins in targeted drug delivery, diagnostic assays, and therapeutics, signaling a paradigm shift in the realm of precision medicine.
Fluorescent Labeling: Serving as a cornerstone in fluorescence imaging and flow cytometry, DBCO-NHS ester 3 assumes a pivotal role in labeling proteins and biomolecules with fluorophores. By binding fluorescent dyes to specific targets, researchers gain unparalleled insights into cellular processes and molecular interactions in real-time, illuminating cell biology, protein localization, and interaction dynamics with unrivaled clarity.
Surface Functionalization: The versatility of DBCO-NHS ester 3 extends to surface modification of nanoparticles, microarrays, and biosensors with bioactive molecules. This critical functionalization of surfaces creates interfaces capable of selectively binding to biomolecular targets, bolstering the sensitivity and specificity of biosensors and diagnostic tools. This process stands as a linchpin in tissue engineering applications, where surface interactions dictate the outcomes desired in the field.
Drug Delivery Systems: Positioned at the forefront of innovation in drug delivery, DBCO-NHS ester 3 propels the development of novel systems by facilitating the attachment of therapeutic agents to polymers or nanoparticles. This strategic attachment ensures the targeted and controlled release of drugs at precise sites, minimally impacting side effects while maximizing treatment efficacy. The pivotal role of DBCO-NHS ester 3 in advancing precision medicine and nanomedicine technologies heralds a new epoch in personalized healthcare.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.