EMCC-Peg8-Lys-PNP

EMCC-Peg8-Lys-PNP Catalog number: BADC-01430

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EMCC-Peg8-Lys-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
EMCC-Peg8-Lys-PNP
Catalog Number
BADC-01430
Molecular Formula
C77H98N10O20
Molecular Weight
1483.68
EMCC-Peg8-Lys-PNP

Ordering Information

Catalog Number Size Price Quantity
BADC-01430 -- $--
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Description
EMCC-Peg8-Lys-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
EMCC-1; EMCC-PEG8-Lys(Mtt)-PAB-PNP
IUPAC Name
4-((S)-35-(4-(((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carboxamido)methyl)-1H-1,2,3-triazol-1-yl)-2-(4-((diphenyl(p-tolyl)methyl)amino)butyl)-4,8-dioxo-6,12,15,18,21,24,27,30,33-nonaoxa-3,9-diazapentatriacontanamido)benzyl (4-nitrophenyl) carbonate
InChI
InChI=1S/C77H98N10O20/c1-58-15-23-64(24-16-58)77(62-10-4-2-5-11-62,63-12-6-3-7-13-63)80-33-9-8-14-69(75(93)81-65-25-19-60(20-26-65)55-106-76(94)107-68-29-27-67(28-30-68)87(95)96)82-71(89)57-105-56-70(88)78-34-36-97-38-40-99-42-44-101-46-48-103-50-51-104-49-47-102-45-43-100-41-39-98-37-35-85-54-66(83-84-85)52-79-74(92)61-21-17-59(18-22-61)53-86-72(90)31-32-73(86)91/h2-7,10-13,15-16,19-20,23-32,54,59,61,69,80H,8-9,14,17-18,21-22,33-53,55-57H2,1H3,(H,78,88)(H,79,92)(H,81,93)(H,82,89)/t59-,61-,69-/m0/s1
InChIKey
BPCVATPJLWWNEK-SSLGMICESA-N

EMCC-Peg8-Lys-PNP, a specialized chemical compound with diverse applications in biomedicine and materials science, unveils intricate properties for a myriad of uses. Here are four key applications of EMCC-Peg8-Lys-PNP:

Targeted Drug Delivery: Through the utilization of EMCC-Peg8-Lys-PNP, researchers pioneer advanced targeted drug delivery systems that redefine therapeutic interventions. The PEGylation process enhances the solubility and stability of therapeutic agents, while the lysine residue provides a strategic site for drug conjugation. This intricate process enables the precise delivery of medications to specific tissues or cells, minimizing adverse effects and maximizing therapeutic efficacy with precision.

Bioconjugation: The versatile functional groups of EMCC-Peg8-Lys-PNP play a pivotal role in bioconjugation techniques that propel the frontiers of diagnostic and therapeutic applications forward. This compound intricately links to proteins, antibodies, or other biomolecules to craft tailored conjugates for a myriad of purposes. Such conjugates find utility in imaging, targeting specific biomarkers, or delivering therapeutic payloads directly to disease sites.

Nanomedicine: Within the domain of nanomedicine, EMCC-Peg8-Lys-PNP emerges as a vital component due to its multifunctionality and advanced properties. The PEG moiety bestows stealth characteristics upon nanoparticles, minimizing immune recognition and clearance from the bloodstream. This sophisticated feature prolongs the circulation time of nanoparticles, facilitating the efficient delivery of drugs or imaging agents to targeted sites.

Biosensing: The adoption of EMCC-Peg8-Lys-PNP in the development of cutting-edge biosensors for detecting specific biomolecules underscores its versatility and complexity. The PEGylated structure of this compound assumes a critical role in mitigating non-specific binding, thereby enhancing the specificity and sensitivity of biosensors to unprecedented levels. This groundbreaking application resonates in clinical diagnostics, environmental monitoring, and research settings, enabling the swift detection of pathogens, proteins, or other analytes with a sophistication mirroring the complexity of biological systems.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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