endo-BCN-PEG4-NHS ester - CAS 2252422-32-3 Catalog number: BADC-01537

endo-BCN-PEG4-NHS ester is a versatile chemical reagent used in bioconjugation and biomedical research. Here are some key applications of endo-BCN-PEG4-NHS ester:

Protein Labeling: endo-BCN-PEG4-NHS ester is commonly used in protein labeling applications due to its ability to specifically react with amines on proteins. By targeting lysine residues, researchers can attach various probes, such as fluorescent dyes, facilitating protein tracking and visualization. This technique is essential for studying protein interactions and localization within cells.

Antibody Conjugation: In antibody conjugation, endo-BCN-PEG4-NHS ester serves as a critical linker between antibodies and other molecules, such as drugs or radioisotopes. This linkage allows for the targeted delivery of therapeutic agents to specific cells or tissues, enhancing treatment efficacy. The reagent’s specificity and stability make it ideal for developing antibody-drug conjugates (ADCs) for cancer therapy.

Drug Delivery Systems: endo-BCN-PEG4-NHS ester is utilized to modify nanoparticles and other drug carriers to improve their biocompatibility and targeting capabilities. By conjugating targeting ligands or therapeutic agents to drug delivery systems, researchers can create more effective treatments with reduced side effects. This application is particularly valuable in the development of targeted cancer therapies and personalized medicine approaches.

Biomolecule Surface Functionalization: The ester is also used in the functionalization of biomolecule surfaces to study interactions with cells and other biomolecules. By attaching specific functional groups to surfaces, researchers can create biomimetic environments to study cell behavior, adhesion, and differentiation. This approach is important for tissue engineering, regenerative medicine, and the development of biosensors.