Catalog Number | Size | Price | Quantity |
---|---|---|---|
BADC-00416 | -- | $-- |
endo-BCN-PEG3-PFP ester, a versatile bifunctional linker molecule, finds extensive utility in bioconjugation and chemical biology. Here are four key applications of endo-BCN-PEG3-PFP ester creatively:
Bioconjugation: Positioned as a cornerstone in scientific pursuits, endo-BCN-PEG3-PFP ester emerges as a crucial player in coupling biomolecules like proteins, peptides, and antibodies through the intricate art of click chemistry. The BCN group engages in selective reactions with azide-functionalized molecules, giving birth to robust triazole linkages. This coupling maneuver, renowned for its efficacy, enables the meticulous assembly of functional bioconjugates tailored for a myriad of diagnostic and therapeutic ventures.
Drug Delivery: Pioneering targeted drug delivery innovations, endo-BCN-PEG3-PFP ester assumes a pivotal role in crafting precision drug delivery systems. By conjugating therapeutic agents to targeting entities, such as ligands or antibodies, this ester facilitates the accurate transport of drugs to specific cellular destinations. This focused delivery mechanism not only enhances treatment efficacy but also mitigates unintended off-target effects and toxicit.
Surface Modification: Venturing into the realm of surface engineering, endo-BCN-PEG3-PFP ester emerges as a crucial contributor in functionalizing surfaces for a myriad of biomedical devices and biosensor applications. Through the strategic attachment of designated biomolecules to azide-functionalized surfaces, this versatile ester enables the creation of bioactive surfaces imbued with tailored characteristics. These modified surfaces have the potential to enhance biocompatibility, elevate sensor sensitivity, or facilitate intricate cell culture experiments, emphasizing the transformative impact of surface modification in biological inquiries.
Chemical Biology Research: Within the dynamic domain of chemical biology, endo-BCN-PEG3-PFP ester assumes a pivotal role in exploring and manipulating biological systems. Harnessing this ester to label biomolecules with fluorophores or affinity tags empowers researchers to precisely monitor and isolate specific proteins or cellular components. This methodical approach, integral to unraveling intricate biological pathways and pinpointing promising drug targets, underscores the indispensable nature of endo-BCN-PEG3-PFP ester in advancing our understanding of the complex mechanisms governing biological processes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.