Catalog Number | Size | Price | Quantity |
---|---|---|---|
BADC-00414 | -- | $-- |
The specialized chemical reagent endo-BCN-PEG4-PFP ester is a linchpin in various scientific applications, particularly in the sphere of bioconjugation. Here we present four key applications of this compound:
Bioconjugation: Serving as the bedrock of bioconjugation, endo-BCN-PEG4-PFP ester facilitates the binding of biological molecules such as proteins or antibodies to other entities via its reactive ester group. This foundational process is imperative for constructing targeted drug delivery systems and diagnostic tools. The incorporation of the PEG4 spacer imparts flexibility and diminishes steric hindrance, ensuring efficacious conjugation and heightened functionality in the resultant bioconjugates.
Drug Delivery: In the realm of cutting-edge drug delivery systems, this compound emerges as a pivotal component where precise targeting of therapeutic agents reigns supreme. The BCN (bicyclo[6.1.0]nonyne) group enables click chemistry with azide-containing molecules, facilitating the coupling of drugs to targeting moieties. This strategic linkage enhances the efficiency and specificity of drug delivery to affected tissues, thereby elevating therapeutic efficacy with pinpoint accuracy.
Surface Functionalization: The utility of endo-BCN-PEG4-PFP ester extends to the functionalization of surfaces such as nanoparticles or biosensors with biological ligands. By modulating surface properties, this technique propels the development of sophisticated biosensing devices, enabling sensitive and selective detection of biomolecules.
Proteomics and Glycomics: In the realms of proteomics and glycomics, endo-BCN-PEG4-PFP ester emerges as an invaluable tool for labeling and capturing specific biomolecules for in-depth analysis. This capability empowers researchers to delve into the structures and interactions of proteins and glycans within intricate biological systems.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.