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m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01167 | -- | $-- | Inquiry |
mPEG11-amine, a versatile polyethylene glycol derivative, finds extensive application in the biosciences. Here are four key applications of mPEG11-amine:
Drug Delivery: Positioned at the forefront of drug delivery innovation, mPEG11-amine serves as a pivotal linker in the creation of drug delivery systems, especially in conjugating therapeutic molecules like peptides and proteins. Its inherently hydrophilic properties enhance drug solubility and stability, prolonging circulation time within the body. This optimization leads to heightened bioavailability and diminished immunogenicity, rendering mPEG11-amine indispensable in pharmaceutical endeavors.
Bioconjugation: Playing a pivotal role in biochemistry and molecular biology, mPEG11-amine emerges as a versatile reagent for diverse bioconjugation techniques. Its utility lies in attaching fluorescent dyes or antibodies to biomolecules, facilitating seamless labeling and detection in a variety of assays and imaging applications. The unique amine group enables precise and robust covalent bonding, ensuring stable conjugation conditions essential for accurate research outcomes.
Surface Modification: Embraced for surface modification strategies, mPEG11-amine contributes significantly to enhancing the biocompatibility and functionality of various materials. By coating surfaces with this compound, researchers effectively curtail protein adsorption and cell adhesion, pivotal aspects in medical device and implant technology. This transformative modification elevates material performance and longevity within biological settings, underscoring its critical role in advancing biomedical technologies.
Protein Stabilization: In the realm of protein research, mPEG11-amine emerges as a stalwart in stabilizing proteins during storage and handling procedures. Its PEG backbone acts as a shield against protein aggregation and denaturation, preserving protein activity and integrity over prolonged durations. This distinctive attribute proves invaluable in bolstering the stability of therapeutic proteins and enzymes, ensuring their optimal efficacy across diverse applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
