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m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01067 | -- | $-- | Inquiry |
mPEG9-amine, a versatile polyethylene glycol derivative, is prized for its chemical properties and finds widespread utility in bioconjugation endeavors. Here are four key applications of mPEG9-amine:
Drug Delivery Systems: Delving into the realm of drug delivery, mPEG9-amine emerges as a pivotal player in modifying drug molecules to heighten their solubility, stability, and bioavailability. Through the attachment of polyethylene glycol (PEG) chains to drugs, researchers can mitigate immunogenic responses and extend circulation time in the bloodstream. This innovative PEGylation approach yields enhanced therapeutic outcomes across a spectrum of pharmaceuticals encompassing anticancer agents and biologics.
Bioconjugation: Pioneering advancements in bioconjugation, mPEG9-amine assumes the role of a connector molecule, facilitating the linkage of functional groups or biomolecules to proteins, peptides, or other macromolecules. This transformative modification journey enhances the pharmacokinetic and pharmacodynamic profiles of biologics.
Surface Modification: Venturing into the domain of surface engineering, mPEG9-amine unfurls its potential in enhancing the biocompatibility of nanoparticles, biomaterials, and medical devices while concurrently curtailing non-specific binding events. The PEG chains act as guardians, erecting a protective shield that fends off unwanted protein adhesion and immune responses.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
